Oligosakkarit denilen küçük şeker zincirlerinden oluşan karbonhidratlar hücre zarındaki protein ve yağlara kovalent bağlarla bağlanarak glikolipid ve glikoprotein denilen yapılar oluştururlar. Bu yapıların hücre zarında oluşturduğu örtüye glikokaliks adı verilir.
Glikokaliks hücrenin kimliği gibidir. Diğer hücrelerle iletişim kurmaya aracı olur. Yani bir ortama karaciğer ve böbrek hücrelerini doldursak, karaciğer hücreleri bir alana böbrek hücreleri bir alana toplanır. Çünkü karaciğer hücreleri birbirini tanır ve bağlanırlar. Yani bir karaciğer hücresinin glikokaliks yapısı böbrek hücresine uymadığı için, böbrek hücresi ile bağlanma gerçekleştirmez.
Normal hücreler büyürken birbirlerine temas ederler, büyümeleri yavaşlar ve aynı anda hepsinin büyümesi durur. Bu olaya kontakt inhibisyon (temas engeli) adı verilir. Bu olay genelde kanser hücrelerinde görülmez çünkü kanser hücreleri bozuk glikokaliks yapısına sahiptirler.
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